Japanmakak-rhadinovirus Kjelder | Navigasjonsmeny«Genomic Characterization of Japanese Macaque...


Herpesviridae


rhadinovirusjapanmakakendemyeliniserande sjukdomenjapanmakakencefalomyelittmultippel skleroserhesusape-rhadinovirusKaposi-sarkom-assosiert herpesvirusmikro-RNA




Japanmakak-rhadinovirus (JMRV) er eit rhadinovirus som nyttar japanmakaken som vert. Det vart funne i arrvev hjå japanmakakar med den demyeliniserande sjukdomen japanmakakencefalomyelitt, ein sjukdom som kan minna om menneskesjukdomen multippel sklerose.[1]


Japanmakak-rhadinovirus er nært i slekt med rhesusape-rhadinovirus. Mellom dei kjende menneskevirusa er det nærast i slekt med Kaposi-sarkom-assosiert herpesvirus.[1]


Genomet til japanmakak-rhadinovirus kodar for fleire mikro-RNA, der fleire er homologe til mikro-RNA frå Kaposi-sarkom-assosiert herpesvirus og rhesusape-rhadinovirus.[2]



Kjelder |




  1. ↑ 1,01,1 Estep, R. D; Hansen, S. G; Rogers, K. S; Axthelm, M. K; Wong, S. W (2012). «Genomic Characterization of Japanese Macaque Rhadinovirus, a Novel Herpesvirus Isolated from a Nonhuman Primate with a Spontaneous Inflammatory Demyelinating Disease». Journal of Virology 87 (1): 512–23. PMC 3536378. PMID 23097433. doi:10.1128/JVI.02194-12. 


  2. ↑ Skalsky, Rebecca L; Barr, Sarah A; Jeffery, Andrew J; Blair, Tiffany; Estep, Ryan; Wong, Scott W (2016). «Japanese Macaque Rhadinovirus Encodes a Viral MicroRNA Mimic of the miR-17 Family». Journal of Virology 90 (20): 9350. PMID 27512057. doi:10.1128/JVI.01123-16. 




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